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Ongoing research focuses on elucidating their molecular mechanisms and optimizing health applications, emphasizing their potential in preventive medicine and holistic wellness strategies (Tables 1, 2)

Strategies that modestly increase both the cytoplasmic [NAD + ]/[NADH] and [NADPH]/[NADP + ] and stimulate mitochondrial NADH-generating pathways or inhibit mitochondrial NADH-oxidizing pathways in astrocytes, oligodendrocytes, and neurons will likely improve metabolic health and decrease oxidative damage to decrease cellular senescence, a driver of brain aging (Zhang et al., 2022)

BOC Sciences' Solution Developed a PEGylated liposome system to provide steric stabilization and prevent aggregation within the gel matrix

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