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In type 2 diabetes, GLP-1 receptor agonists can stimulate the pancreas to release more insulin and slow digestion to mitigate blood sugar spikes and drops

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1 Introduction The idea that substances produced by duodenal mucosa could stimulate and initiate pancreatic endocrine, thereby reducing the amount of urinary glucose in patients with diabetes, was first proposed in 1906 (Moore, 1906)

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