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Results of a meta-analysis that analyzed 19 trials suggested that grape seed extract may have blood pressure and heart rate lowering properties 15 The effect of grape (Vitis vinifera) seed extract supplementation on flow-mediated dilation, blood pressure, and heart rate: A systematic review and meta-analysis of controlled trials with duration- and dose-response analysis | Foshati et al

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This can inadvertently lead to weight loss and improve overall health outcomes

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Therefore, an incomplete diet, physiological stress situations and some clinical cases can create a need for external LC supplementation [13]