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Communicating this principle to patients early can shape expectations, reduce anxiety, and improve overall tolerability

Clinicians should screen for history of pancreatitis, severe gastrointestinal disease (particularly severe gastroparesis), diabetic retinopathy (particularly if intensifying glycemic control rapidly), and gallbladder disease, as these conditions may influence treatment decisions or require closer monitoring

With increasing dose administration over prescribed dose, increasing amounts of nafamostat block trypsin release of oxycodone and prevent opioid overdose

AstraZeneca and Amgens Tezspire (tezepelumab) has been approved in the US as an add-on maintenance treatment for adults and adolescents (12+) with inadequately controlled chronic rhinosinusitis with nasal polyps (CRSwNP) marking a major advancement for patients living with this epithelial-driven inflammatory condition

Once-weekly semaglutide doubles the five-year risk of nonarteritic anterior ischemic optic neuropathy in a Danish cohort of 424,152 persons with type 2 diabetes