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Enzymatic cleavage of albumin results in less efficient FcRn-mediated rescue from lysosomal degradation and, consequently, a dramatically shorter plasma half-life of 3.5 days in humans 60

These findings offer hope for patients and healthcare providers seeking additional treatment options for binge eating symptoms, especially for people living with obesity

Kessler RC, Petukhova M, Sampson NA, Zaslavsky AM, Wittchen H-U

Something about these medications directly protects the heart and blood vessels

The future of GLP-1 research As GLP-1s continue to reshape the treatment of type 2 diabetes and obesity (along with an expanding list of potential indications), real-world evidence will be essential for optimizing their use, ensuring access, and tailoring treatments to the individual needs of patients