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In some embodiments formulations described herein comprise crystalline particles

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However, conditions affecting the gastrointestinal tractincluding pernicious anaemia, Crohn's disease, coeliac disease, or gastric surgerycan significantly impair absorption, necessitating alternative supplementation routes such as intramuscular hydroxocobalamin injections, which deliver B12 directly into the bloodstream

Neelakantan H, Brightwell CR, Graber TG, et al

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