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We also note that the flux around the methionine cycle is 205 M/hr and approximately half enters the transsulfuration pathway (V CBS = 103 M/hr) and half is remethylated to methionine in accordance with the results of Finkelstein and Martin [22]

Except for the beneficial effects in the model animals fed normal diets, LA treatment with the same dose significantly attenuated hepatic TG accumulation (via increasing ACC and decreasing FAS) in gene-mutant obesity animals fed an HFD (40% energy from fat) and high-cholesterol diet [88]

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