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Four hormones dominate appetite regulation: ghrelin drives hunger, while leptin, GLP-1, and peptide YY signal fullness through different mechanisms and timescales

DISCUSSION In this large US population-based PS matched cohort of patients with diabetes and on metformin, we found that GLP-1RA use was associated with a lower risk of incident AF compared with DPP4i, but no difference compared with SGLT2i

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