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Individuals with MTHFR variants may rely more heavily on active B12 forms like methylcobalamin or adenosylcobalamin, depending on methylation response

However, the capacity of SUMPs and other similar mobility planning instruments in bringing about effective changes towards more sustainable and just mobility practices has been questioned (Maltese, Gatta and Marcucci, 2021

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While the available research suggests that this peptide blend is well-tolerated with minimal side effects, further studies are needed to fully understand its long-term safety and efficacy