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Most considerations of non-animal alternatives for skin irritation/sensitization testing tend to examine a single aspect of the process (e.g., chemical reactivity, epidermal bioavailability, dendritic cell responses)
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Considering the generally recognized relationship of CCl 4 with free radical formation and lesion development, the beneficial effects of NaBPC157 appear also to apply to other free radical induced organ lesions, in particular, irradiation
Yeast cells (2 10 7 ) were seeded in plates (10 cm) with 10 ml of RPMI medium in the presence of M3 (at concentrations of 12.5 M and 25 M), M4 (at concentrations of 1.2 M and 2.1 M) and without peptide