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7 days later, anesthetized mice were anesthetized and colon tissues were taken to observe pathological changes in the colon of mice by HE staining, the expression of myeloperoxidase (MPO), glutathione peroxidase 4 (GPX4), and ferritin heavy chain (FTH) was detected by immunohistochemistry
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As in lean PAR2-G37I mice postprandial GIP levels (Figure 3G) but not GLP-1 levels (Figure 3H) were significantly reduced in obese PAR2-G37I mice of both sexes
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