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Adv Ther

Here we emphasize the role of Nrf2 activators and the vital role of antioxidants like the GSH system in prevention against oxidative stress and cell and tissue damage (Cuadrado et al., 2020) in SARS-CoV-2 infection and COVID-19 disease (Figure 5)

Setting: Clinic vs

Hua S (2020) Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract - Influence of Physiological, Pathophysiological and Pharmaceutical Factors

In db/db mice, administration of M-920, a caspase inhibitor, reduced renal CASP1, IL-1, IL-18, and NLRP3 inflammasome activation, leading to amelioration of albuminuria and renal ECM accumulation (198)