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Although insomnia is not listed as a primary or frequent side effect in clinical trials, a few mechanisms may explain sleep disturbances: Gastrointestinal Discomfort Nausea, bloating, or acid reflux common side effects of semaglutide may interfere with sleep, especially if the medication is taken late in the day

Frequently Asked Questions Can I use my GLP-1 injection if it has been left out of the fridge overnight

Semaglutide, while not a diuretic, frequently causes gastrointestinal side effects such as nausea, vomiting, or diarrhea, especially when you are first starting the medication or increasing your dose

Semaglutide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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