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While tightly regulated under normal conditions, Ca homeostasis becomes profoundly dysregulated during myocardial infarction (MI), heart failure, ischemiareperfusion injury, cardiac hypertrophy, and atherosclerosis, resulting in pathological signaling, organellar stress, and cardiomyocyte death

Evidence of a functional role for the cyclin-dependent kinase-inhibitor p21WAF1/CIP1/MDA6 in promoting differentiation and preventing mitochondrial dysfunction and apoptosis induced by sodium butyrate in human myelomonocytic leukemia cells (U937)

23 , 428A (2012)

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Results showed significantly accelerated and increased bone formation in non-healing femoral defects compared to uncoated scaffolds and empty defects