Feb 2023;25(2):407-416
While Glutathione is generally considered safe, it can potentially interact with other medications
Peer-reviewed clinical literature indexed in PubMed and PubMed Central was searched with terms including: microneedling, microinfusion, percutaneous collagen induction therapy, transdermal drug delivery, hollow microneedle, GHK-Cu, copper tripeptide, Acetyl Hexapeptide-8, Argireline, polydeoxyribonucleotide, PDRN, epidermal growth factor, rhEGF, sh-Oligopeptide-1, hyaluronic acid molecular weight, niacinamide, Centella asiatica, AquaGold, mesotherapy
Operational steps: Take 0.5 mL of glutathione standard solution or sample solution to be tested (0.1 ~ 3.0 mol/L), add it to 1.5 mL of 0.15 mol/L NaOH solution, then add 0.5 mL of 3% formaldehyde solution
Reported issues, usually mild, include redness, itching, or contact sensitivity, particularly when GHK-Cu is combined with strong actives like retinoids or exfoliating acids