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Appetite Suppression Some users report appetite suppression as a potential side effect of the use of Melanotan peptides

Most patients notice changes in appetite and early satiety within the first week of starting GLP-1 therapy

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Specifically, GLP-1 activates pro-opiomelanocortin (POMC) neurons, which promote satiety, whilst inhibiting neuropeptide Y (NPY) and agouti-related peptide (AgRP) neurons, which typically stimulate appetite

Finally, cognition also declines with advancing age, particularly those cognitive functions that involve novel problem solving and psychomotor processing speed, with its own related impact on the older individuals ability to function independently