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Safety concerns included uncharacterized immunogenicity (the risk that injected peptides trigger immune reactions), inadequate impurity and endotoxin testing in available raw material, the unresolved free base versus acetate salt form distinction, and, for BPC-157 specifically, an angiogenesis mechanism that raises theoretical cancer-risk concerns for certain patient populations

For optimal long-term preservation, materials may be stored frozen

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Neutrophil extracellular trap formation and extracellular DNA in sputum of stable COPD patients