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Quick Answer: GLP-1 receptor agonist-related fatigue likely results from multiple indirect mechanisms including substantial caloric restriction, gastrointestinal side effects causing dehydration and nutritional deficits, and metabolic adaptation during weight loss, rather than a single direct pharmacological effect

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Allow several weeks for noticeable benefits, particularly for skin health

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The GLP-1 provision is one part of an agreement that State Treasurer Brad Briner says will lead to hundreds of millions of dollars for the 750,000 state workers, retirees and their families covered by the State Health Plan