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A commenter requested that several cases be excluded or stratified, such as those involving malignancy, infection, fracture, major structural abnormalities, urgent neurologic compromise, prior spine surgery, implanted hardware (including spinal cord stimulators or fusion constructs), ( failed comprehensive conservative care with documented non-response to multimodal therapy, and non-spinal mimics

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Whether Southend Pharmacy and Boothwyn Pharmacy operate under the 503A patient-specific compounding framework or the 503B outsourcing-facility framework wasn't stated in the materials reviewed, and it's relevant given the active FDA rulemaking on 503B bulk compounding of these exact medications discussed earlier in this article