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Nonetheless, uncontrolled input signal during aging may cause chronic proinflammatory conditions that are conducive to various chronic diseases (Fougre et al., 2017)

Exp Physiol 2007

It is best to talk to a healthcare provider right away if any of the following appear: The eyes or skin turn yellow Urine becomes dark for more than a day Stools become pale or gray Ongoing nausea or vomiting Sudden or serious fatigue Pain near the liver (right upper belly) Waiting too long can allow a mild liver issue to become serious