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93,94 Despite the knowledge that redox perturbations accompany pulmonary diseases like cancer, pulmonary fibrosis, and acute lung injury, little is known about the role of Prxs in the etiology of these diseases

The results from a 48-week phase 2 trial in patients with obesity who are at risk of developing cardiovascular diseases, showed that patients had achieved a mean weight loss of 15.6% on a 2.4 mg dose of the drug, and notably, improvements in blood pressure as well as no cardiac event imbalances took place

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The pathophysiologic pathways in MetS connected to several diseases have been investigated