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Chronic deficiencies may require ongoing treatment

Research published in Endocrinology demonstrated that both human growth hormone and AOD-9604 significantly increased the expression of beta-3 adrenergic receptors in adipose tissue, restoring suppressed receptor levels in obese animal models to match those in lean controls

In animal experiments, obese mice treated with 5-Amino-1MQ lost approximately 5.1% of their body weight over 11 days, without a decrease in food intake, suggesting that its effect is mainly due to metabolic changes rather than appetite suppression