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Secondly, TSH predominantly reflects pituitary sensitivity to circulating T4, rather than tissue-specific availability or utilisation of the active hormone T3

The delivery method (like liposomal) is more important for raising blood levels than the total dose in a standard capsule

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doi: 10.3389/fmicb.2025.1606001

As an anti-inflammatory KPVs anti-inflammatory mechanism of action isnt fully understood, but it may have to do with a signaling pathway called NF-B