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If you aren't losing weight on topiramate, your dose may be too low or you may be a clinical "non-responder"

Hypersensitivity reactions may manifest in various ways, ranging from local injection site reactions such as erythema, swelling, and pruritus to more severe systemic reactions including angioedema, anaphylaxis, or generalized urticaria

WHAT DOES THE RESEARCH SAY

Or they dont want to experience side effects while on a trip

The needle itself is very thinsimilar to insulin syringes used by diabetics for decadesbut individual variation in skin thickness, blood vessel positioning, and tissue hydration affects how much visible bleeding occurs