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Interaction of oxidative stress, astrocyte swelling and cerebral ammonia toxicity

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Update 18 , 703713 (2012)

GLP-1 agonists stimulate insulin release, slow down gastric emptying, and reduce appetite by acting on GLP-1 receptors in the brain

However, another systematic review concluded that the evidence for NAC as a treatment for addiction is rather limited and pointed out that although several controlled studies have reported significant results for cocaine, the largest and best-designed trial was positive versus placebo only in a small subgroup of participants, who were abstinent at the beginning of the trial [5]