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2 Overview of osteoarthritis and ferroptosis 2.1 Pathogenic mechanisms of osteoarthritis OA is a common degenerative joint disease marked by gradual cartilage degradation, destruction of subchondral bone structure, synovial inflammation, and clinical symptoms such as joint pain

Without sufficient cysteine from sources like NAC, the body's antioxidant defenses quickly become depleted, leaving cells vulnerable to premature death and structural degradation

Gently swirl the vial (do not shake) until the powder fully dissolves

Antioxidants 12 , 149 (2023)

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