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They exist in a regulatory gray area, often sold with labels that say "for research purposes only." This matters for a few reasons: Quality control is inconsistent

W.SatoH.et al (2006)

doi: 10.1038/s41514-023-00124-2

Deoxynucleoside phosphoramiditesa new class of key intermediates for deoxypolynucleotide synthesis

The systemic administration of lipopolysaccharides (LPS), which are PAMPs of the membrane of gram-negative bacteria, can experimentally induce an acute phase reaction, resulting in a high energy demand for the immune system (10)

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