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The procoagulant effect induced by ouabain is dose- and time-dependent, less pronounced than the collagen-induced response, and significantly reduced in the absence of extracellular Na + or in hyperosmolality (Tomasiak et al., 2007)

Its primary role is to accelerate healing, reduce inflammation, and promote angiogenesis (new blood vessel growth)

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Poly (N-(2-hydroxypropyl) methacrylamide polymer) (pHPMA)-coated penetratin-insulin complex that has almost neutral surface charge showed enhanced mucus diffusion and insulin delivery in a diabetic rat model compared to nanoparticles whose surface charge is negative (Shan et al., 2015)

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