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In addition, while a number of the agonists in Table 1 (Families 2-5) have norleucine at Rj, or an amino acid residue, in the practice of various embodiments of this invention a number of an amino acid residues (D or L) may be used at residue Ri, including without limitation, tyrosine, phenylalanine, aspartic acid, arginine, isoleucme, serine, histidine, glycine, cysteine, methionine, tryptophan, norvaline, ornithine, S-benzyl cysteine amino acid residues

Most published data comes from animal and laboratory studies, and human clinical trials are lacking, so human efficacy is not established [1]

FAQ What is vitamin B12 and why is it important for the body

This is established fact, supported by the SURMOUNT trial series with thousands of participants

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