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Patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 micrograms per kg per day, accumulate aluminum at levels associated with central nervous system and bone toxicity

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The immune system reacts to these proteins, and in few people, those proteins look surprisingly similar to the stomach tissue itself

A preclinical safety study in Regulatory Toxicology and Pharmacology found BPC-157 well-tolerated with no severe toxic effects in mice, rats, rabbits, and dogs