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(Many people use Ozempic off label for weight loss, though it is not FDA-approved for such.) These medications seem to promote weight loss through two mechanisms that, again, mimic the action of endogenous GLP-1: They delay gastric emptying: The sensation of fullness caused by slower gastric emptying can prompt people to eat less, thus helping them lose weight over time

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Sikiric, P., Gojkovic, S., Krezic, I., Smoday, I

doi: 10.1056/NEJMoa2401943 16 SandsdalRMJuhlCRJensenSBKLundgrenJRJanusCBlondMBet al