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These landmark studies, required by regulatory authorities including the EMA and MHRA , have provided reassuring evidence about the cardiovascular safety profile of this drug class

The implications of this simple experiment are profound: cells in the small intestine can secrete factors (named hormones in 1905) that regulate pancreatic function and glucose metabolism

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[DOI] [PubMed] [Google Scholar] 406.Ambler WG, Kaplan MJ

These medications slow gastric emptying, enhance insulin secretion in response to meals, and suppress glucagon release