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Localized application focuses on injured areas (tendon strain, muscle tear), while systemic use supports overall recovery balance

Distinction From Other Mitochondrial Peptides While Humanin primarily protects against cell death in neural and cardiac models, MOTS-C peptide broadly enhances metabolic homeostasis by targeting AMP-activated protein kinase, or AMPK, and antioxidant pathways

Specifically, studies have shown that the loss of mTOR-dependent autophagy pathways impairs synaptic pruning which further underscores immune dysregulation as a contributor to the development of ASD [8,9]

4.2 Respiration rate The post-harvest condition of edible mushrooms is notably influenced by their respiration rate, as the availability of oxygen in the surrounding air directly impacts their metabolic and respiratory activity, as evidenced by Abdelshafy et al