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Central administration of GLP-1 and GIP decreases feeding in mice

And based on the overwhelming clinical evidence and our own extensive experience, GLP-1 medications are the most powerful tool available for that specific objective

Beyond their role in weight reduction, which itself can lessen mechanical friction and inflammation in intertriginous areas, GLP-1s improve insulin sensitivity, cardiometabolic risk factors, and may reduce systemic inflammationall of which can be more prevalent in HS patients

World journal of gastroenterology 19 , 40534059, doi:10.3748/wjg.v19.i25.4053 (2013)

105 Dulaglutide is the first large-molecule GLP-1RA, and the weekly dosing frequency of dulaglutide can greatly improve patient compliance