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Repetition across animal models may strengthen a preclinical hypothesis

Distinction From Other Mitochondrial Peptides While Humanin primarily protects against cell death in neural and cardiac models, MOTS-C peptide broadly enhances metabolic homeostasis by targeting AMP-activated protein kinase, or AMPK, and antioxidant pathways

PLoS One 8(10):e75060 Lenard A et al (2015) Endothelial cell self-fusion during vascular pruning

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