As blood osmolarity decreases, the hypothalamic osmoreceptors sense the change prompting a corresponding decrease in the secretion of ADH
This new study adds to a growing body of evidence that GLP-1 medicines may play a role in lowering dementia risk. After applying matching methods to control for confounding factors, the study included over 174,000 patients, evenly divided between the two treatment groups
however, immunohistochemistry (IHC) investigations revealed decreased expression of IGF-1, 8-OHdG, and ARs in both tumor and adjacent normal tissues
Sambuco, Bradley, et al., 2025)
Several years later, the term MASLD was proposed, and its diagnosis can be done based on the patient meeting one of five cardiovascular risk factors, unlike MAFLD, which underlines a requirement that the patients meet two of seven parameters of metabolic dysfunction (5)