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For type 2 diabetes, NICE guidance (NG28) recommends GLP-1 RAs based on individual factors including comorbidities, prior treatments, and HbA1c targets

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doi: 10.2522/ptj.20130597 [DOI] [PMC free article] [PubMed] [Google Scholar] 51

In one study, participants who followed an exercise programme maintained their weight even a year after the programme ended, while those who relied on medication alone were more likely to regain weight.[8] Current guidance from the World Health Organisation recommends aiming for at least 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity physical activity per week, plus two sessions of muscle-strengthening exercises.[9] Research shows that people who receive continued professional support after losing weight are more likely to maintain their results long-term.[10] When you come off GLP-1 medication, appetite, routine and motivation can all begin to shift, and working with a healthcare professional, dietitian or fitness specialist can help you navigate this transition

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