What the research shows about tirzepatide and lean mass A systematic review published in 2025 examining tirzepatide effects on skeletal muscle mass found that lean tissue loss accounts for 20% to 34% of total weight lost during treatment
As such, they conclude: Our findings extend previous anecdotal safety signals and provide more systematic evidence to inform clinical awareness of this potential adverse effect. Reference: Tang H, Zhang B, Lu Y, Zhang D, Liu R, Lu Y et al
Find out if older adults who walk or hike should take a multivitamin, vitamin C, vitamin D, or other supplements, like electrolytes, when hiking
Eating at consistent times matters tooskipping meals and erratic patterns blunt your GLP-1 response over time (this is one of the reasons I dont recommend intermittent fasting for most women)
AHIP Voluntary Commitments (Now in Effect)