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FOXO4-DRI Potential Selectivity As mentioned, FOXO4-DRI is believed to selectively disrupt the binding of FOXO4 to p53, which may lead to the activation of p53, which in turn may stimulate the process of removing senescent cells

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The 2-Cys PRXs operate through the formation of a homodimer, in which a disulfide bond connects a peroxidatic Cys (C P ) 175 from one monomer and is connected to the resolving Cys located on the second monomer

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