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17 It has been revealed that the inflammation has an important role in the pathogenesis of CS, and various inflammatory markers have been investigated as predictors of the disease

For example, BDHI 18 showed preferential engagement with the active site C126 among the four reactive cysteines (C119, C126, C196, and C413) found in the mitochondrial acetyl-CoA acetyltransferase (ACAT1, Figure S7A)

The filtrates were subjected to LC-MS/MS using a 3200 QTRAP system (AB SCIEX, Framingham, MA) as previously described

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doi:10.1590/S1516-89132013000500017 Ask M, Mapelli V, Hck H, Olsson L, Bettiga M (2013) Engineering glutathione biosynthesis of Saccharomyces cerevisiae increases robustness to inhibitors in pretreated lignocellulosic materials