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The Journal of Physiology, 591, 4655-4666

Danuglipron (from Pfizer) showed mixed results and faced development challenges

Giorgi C, Baldassari F, Bononi A, Bonora M, De Marchi E, Marchi S, et al

Comprehensive Cardiovascular Risk Reduction: Beyond weight loss, retatrutide reduces non-HDL cholesterol, triglycerides, high-sensitivity C-reactive protein, and systolic blood pressure addressing multiple cardiovascular risk factors simultaneously through mechanisms that include but extend beyond weight reduction

At this time, however, these conclusions are limited to speculation given the nature of a single case report