Decreased vitamin B12 absorption due to altered gut microbiota Potential for megaloblastic anemia in prolonged use Increased risk of neuropathy and other neurological complications Dose and Duration Considerations The risk of B12 deficiency with metformin depends on the dose and how long you take it
Zhang, Y., & Hartemink, A
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, et al
or black, tarry stools (digested blood) Tan, greasy, oily stools Worms or tapeworm segments (appear like small grains of rice) Large amounts of undigested food or non-food items (fabric, fragments of toys, etc.) Any of these findings should be investigated by a veterinarian
It also decreases the incidence of active colitis