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Osteoarthritis and Pain Benefits The TRIUMPH-4 trial was designed not only to measure weight loss but also to evaluate whether that weight loss translated into meaningful improvements in knee osteoarthritis pain and physical function

Fortin and Roitman, 2017) with similar effects on cocaine, amphetamine (Egecioglu et al., 2013b), ethanol (Srensen et al., 2016

For most patients, these effects are mild and temporary, but its important to understand what might occur

But it raises a question that the trials themselves highlighted: of the weight lost, 26% to 40% came from lean tissue , not fat

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