Investigating incretin-based therapies as a novel treatment for depression in type 2 diabetes: findings from the South London Diabetes (SOUL-D) Study
Dysregulation and accumulation of free iron causes oxidative stress-dependent damage to neurons in the CNS, resulting in neurological diseases, including epilepsy ( Emerging studies have shown the levels of cell GSH and the labile iron pool are intimately linked ( 2+ in unstable iron pools, it binds to Fe 2+ to prevent lipid peroxidation, directly inhibiting GSH biosynthesis and triggering ferroptosis ( 2 O 2 and protein synthesis-dependent
Most women experience return of normal menstrual function once weight stabilises and adequate nutrition is maintained
Growth Opportunities and Strategic Analysis 7
N Engl J Med 377:644657 Wiviott SD, Raz I, Bonaca MP, Mosenzon O, Kato ET, Cahn A, Silverman MG, Zelniker TA, Kuder JF, Murphy SA, Bhatt DL, Leiter LA, McGuire DK, Wilding JPH, Ruff CT, Gause-Nilsson IAM, Fredriksson M, Johansson PA, Langkilde AM, Sabatine MS (2019) Dapagliflozin and cardiovascular outcomes in type 2 diabetes