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Avoid repeated freeze-thaw: each freeze-thaw cycle creates ice crystal shear stress on the peptide backbone and concentrates solutes during freezing, accelerating aggregation and oxidation

Under physiologic conditions, insulin promotes amyloid- protein clearance thereby preventing its accumulation (Mullins et al., 2017)

GSH is covalently linked at the Cys24 residue) and hGSTO2 (PDB code 3Q19

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