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(Cont'd) Test Organism Metabolic Dose range Mutagenic Reference activation (+ or -) potential Mammalian cells Gene mutation Chinese hamster V79 + and - 0.3 g/ml negative Banzer (1977c) mouse fibroblast + and - 0.03 g/ml negative BALB/3T3 Chromosome Chinese hamster - 0.03-0.3 g/ml positive Mizens et al

Monocytes were purified from PBMC using a negative selection Human Monocyte Isolation Kit (StemCell Easy Sep)

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Its leaves and buds contain rich essential oils with components like limonene, alpha- and beta-pinene, carene, and bornyl acetate

A standard weight-management titration reference (based on FDA-approved Wegovy protocol): Weeks 14: 0.25 mg once weekly Weeks 58: 0.5 mg once weekly Weeks 912: 1.0 mg once weekly Weeks 1316: 1.7 mg once weekly Week 17 onward: 2.4 mg once weekly (maintenance for obesity) For T2DM glycemic control, lower maintenance doses (0.52.0 mg weekly) are used per Ozempic labeling