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Boora added, "Weight regain can happen, but how much partly depends on the habits people have built while on the medication." Sainikhil Sontha, a research associate at Boston University School of Public Health, warned in a statement, "Stopping [treatment] early may mean missed opportunities to prevent heart attacks, kidney disease progression and other complications." Why People Stop Taking GLP-1 Drugs The study also highlighted several factors linked to why people discontinue treatment