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Maintains integrity in gastric juice (pH 1-2) and extreme pH conditions

Intake of higher doses doesnt appear to be associated with detrimental health problems.2 The VNDPG recommends the following B12 guidance2: All vegetarians, regardless of type, should periodically be screened for B12 deficiency, using either methylmalonic acid (MMA) or TCII (transcobalamin) assessment

2.4 Sample preparation For LCQTOF-MS/MS analysis, 1 mg of powder or homogenized tablet was dissolved or extracted using 5 mL of a 1:1:1 (v/v/v) mixture of water/methanol/acetonitrile, assisted by ultrasonication for 10 min, and afterwards filtered by a Whatman 0.2 m pore size polytetrafluoroethylene (PTFE) filter medium (GE Healthcare, Chicago, IL, United States)

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