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In conclusion, SJS/TEN is a rare but severe systemic drug adverse reaction, mostly involving generalized skin and mucosa

Compared to APOE3 and APOE2, APOE4-mediated pathways of A clearance are impaired, and APOE4 exhibits a higher affinity interaction with A, potentially driving a more severe A plaque burden, 119,121,123 making it one of the strongest genetic risk factors for AD

Sans entrer dans les dtails de laspect chimique de loxydo-rduction (redox), une substance qui peut se dpartir dun lectron pour un diminuer le nombre total est dite rductrice