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Other conditions like obstructive sleep apnea and chronic kidney disease can further complicate blood pressure control

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In 2026, the FDA will also decide on approval for Novo Nordisks combination treatment CagriSema, which mixes semaglutide with cagrilintide, a mimic of the hunger-related hormone amylin, for a more potent weight loss effect

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Research on the Mounjaro and retatrutide trials suggests this typically accounts for around a quarter of total weight loss, similar to whats observed with other forms of significant weight reduction